Logo

 

Home People Research Publication Glossary Contacts

______________________________________________

 

Cryosurgical Devices and Techniques

Rabin, Y., Shitzer, A. (1996): A new cryosurgical device for controlled freezing, Part I: Setup and validation test. Cryobiology, 33:82-92. Article (PDF 0.2MB)

Rabin, Y., Coleman, R., Mordohovich, D., Ber, R.,  Shitzer, A. (1996): A new cryosurgical device for controlled freezing, Part II: In vivo experiments on rabbits’ hind thighs. Cryobiology, 33:93-105. Article (PDF 2.1MB)

Rabin, Y., Julian, T.B., Wolmark, N. (1997): A compact cryosurgical apparatus for minimal-invasive cryosurgery. Biomedical Instrumentation & Technology, 31:251-258. Article (PDF 1.3MB)

Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1998): Evaluation of post cryosurgery injury in a sheep breast model using the vital stain 2,3,5-triphenyltetrazolium chloride. CryoLetters, 19(4):255-262. Article (PDF 2.6MB)

Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1999): Long-term follow-up post-cryosurgery in a sheep breast model. Cryobiology, 39:29-46. Article (PDF 0.6MB)

Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1999): Cryosurgery for breast malignancies: apparatus and techniques. In: Advances in Heat and Mass Transfer in Biotechnology. ASME IMECE 1999, Nashville, Tennessee. HTD-Vol. 363, BED-Vol. 44, pp. 65-70 Article (PDF 1.6MB)

Rabin, Y., Julian, T.B., Wolmark, N. (1999): Method and apparatus for heating during cryosurgery. US Patent No. 5,899,897 Patent (PDF 1.4MB)

Rabin, Y., Julian, T.B., Wolmark, N. (2000): Method and apparatus for minimal-invasive cryosurgery. US Patent No. 6,039,730 Patent (PDF 1.6MB)

Rabin, Y. (2001): Imaging of breast cryosurgery. In: Atlas of Cryosurgery (Korpan, N.K., Ed.), Springer-Verlag, Vienna, Austria, pp. 344-353. Article (PDF 4.7MB)

Rabin, Y., Julian, T.B., Olson, P. (2001): Minimally invasive breast cryosurgery. In: Basics of Cryosurgery (Korpan, N.K., Ed.), Springer-Verlag, Vienna, Austria, pp. 213-223. Article (PDF 10.3MB)

Rabin, Y., Julian, T.B., Wolmark, N. (2004): Method and apparatus for cryosurgery. US Patent No. 6,786,902 B1 Patent (PDF 1.2MB)

Computerized Planning of Cryosurgery

Rabin, Y., Stahovich, T.F. (2003): Cryoheater as a means of cryosurgery control. Physics in Medicine and Biology, 48:619-632. Article (PDF 0.4MB)

Lung, D.C., Stahovich, T.F., Rabin, Y. (2004): Computerized planning for multiprobe cryosurgery using a force-field analogy. Computer Methods in Biomechanics and Biomedical Engineering, 7(2):101-110. Article (PDF 0.3MB)

Rabin, Y., Lung, D.C., Stahovich, T.F. (2004): Computerized planning of cryosurgery using cryoprobes and cryoheaters. Technology in Cancer Research & Treatment, 3(3):229-243. Article (PDF 1.1MB)

Tanaka, D., Shimada, K., Rabin, Y. (2006): Two-phase computerized planning of cryosurgery using bubble-packing and force-field analogy. ASME Journal of Biomechanical Engineering, 128(1):49-58. Article (PDF 3.0MB)

Rossi, M.R., Tanaka, D., Shimada, K., Rabin, Y. (2006): An efficient numerical technique for bioheat simulations and its application to computerized cryosurgery planning. Computer Methods and Programs in Biomedicine, 85(1):41-50 Article (PDF 0.7MB)

Tanaka, D., Rossi, M.R., Shimada, K., Rabin, Y. (2007): Towards intra-operative computerized planning of prostate cryosurgery. The International Journal of Medical Robotics and Computer Assisted Surgery, 3:10-19 Article (PDF 0.9MB)

Rossi, M.R., Rabin, Y. (2007): Experimental verification of numerical simulations of cryosurgery with application to computerized planning. Physics in Medicine and Biology, 52:4553-4567 Article (PDF 0.9MB)

Tanaka, D., Shimada, K., Rossi, M.R., Rabin, Y. (2008): Cryosurgery planning using bubble packing in 3D. Computer Methods in Biomechanics and Biomedical Engineering, 11(2):113-121 Article (PDF 0.3MB)

Tanaka, D., Shimada, K., Rossi, M.R., Rabin, Y., (2008): Computerized planning of prostate cryosurgery with pullback procedure. Computer Aided Surgery, 13(1):1-13 PubMed

Rossi, M.R., Tanaka, D., Shimada, K., Rabin, Y., (2008): Computerized planning of cryosurgery using bubble packing: an experimental validation on a phantom material. The International Journal of Heat and Mass Transfer, 51:5671-5678 Article (PDF 0.6MB)

Rabin, Y. (2008): Key issues in bioheat transfer simulations for the application of cryosurgery planning. Cryobiology, 56(3):248-50 Article (PDF 0.1MB)

Rabin, Y. (2009): Computerized planning of cryosurgery: from model reconstruction to cryoprobe placement strategies. BiOS 2009, Energy-based Treatment of Tissue and Assessment V, San Jose, CA, USA (January 24-29) (Invited Lecture) Article (PDF 0.6MB)

Rossi, M.R., Tanaka, D., Shimada, K., Rabin, Y. (2010): Computerized planning of prostate cryosurgery using variable cryoprobe insertion depth. Cryobiology, 60(1):71-79 PubMed

Computerized Training of Cryosurgery

Shimada, K., Furuhata, T., Song, I., Sehrawat, A., Rabin, Y. (2011): Generation of 3D Prostate Models for Computerized Cryosurgical Trainer. CRYO2011-the 48th Annual Meeting of the Society for Cryobiology, Corvallis, OR. Cryobiology, 63(3):315-316

Sehrawat, A., Shimada, K., Rabin, Y. (2012): Generating prostate models by means of geometric deformation for the application of computerized training of cryosurgery. International Journal of Computer Assisted Radiology and Surgery Article (PDF 1.0MB)

Keelan, R., Yamakawa, S., Shimada, K., Rabin, Y. (2012): Computerized Training of cryosurgery – a system approach. Cryoletters, in press

Rabin, Y. (2012): Computation tools in the service of cryosurgery, Society for Thermal Medicine Annual Meeting, Portland, OR (April 13-16); Refresher Course

Mathematical Modeling of Phase Change Problems

Rabin, Y., Korin, E. (1993): An efficient numerical solution for the multidimensional solidification (or melting) problem using a microcomputer. International Journal of Heat and Mass Transfer, 36(3):673‑683. Article (PDF 1.1MB)

Rabin, Y., Shitzer, A. (1995): Exact solution to the one‑dimensional inverse Stefan problem in non‑ideal biological tissues. ASME Journal of Heat Transfer, 117(2):425-431. Article (PDF 1.2MB)

Rabin, Y., Shitzer, A. (1997): Combined solution to the inverse Stefan problem for successive freezing/thawing in non‑ideal biological tissues. ASME Journal of Biomechanical Engineering, 119(2):146-152. Article (PDF 1.4MB)

Rabin, Y., Shitzer, A. (1998): Numerical solution of the multidimensional freezing problem during cryosurgery. ASME Journal of Biomechanical Engineering, 120(1):32-37. Article (PDF 1.4MB)

Rabin, Y., Maytal, B-Z. (1999): Thermal analysis of cryocycling. CryoLetters, 20(2):95-102. Article (PDF 0.5MB)

Rabin, Y. (2000): The effect of temperature-dependent thermophysical properties in heat transfer simulations of biomaterials in cryogenic temperatures. CryoLetters, 21:163-170. Article (PDF 0.8MB)

Rabin, Y., Stahovich, T.F. (2002): The thermal effect of urethral warming during cryosurgery. CryoLetters, 23:361-374. Article (PDF 0.2MB)

Rossi, M.R., Rabin, Y. (2007): Analysis of a numerical scheme for bioheat simulations of cryosurgery and its experimental validation on a phantom material. MSV'07- The 2007 International Conference on Modeling, Simulation and Visualization Methods, Las Vegas, Nevada, USA (June 25-28) Article (PDF 0.2MB)

Solid Mechanics Aspects of Low-Temperature Biology

Rabin, Y., Steif, P.S. (1996): Analysis of thermal stresses around a cryosurgical probe. Cryobiology, 33:276-290. Article (PDF 0.3MB)

Rabin, Y., Steif, P.S. (1998): Thermal stresses in a freezing sphere and its application to cryobiology. ASME Journal of Applied Mechanics, 65(2):328-333. Article (PDF 0.9MB)

Rabin, Y., Steif, P.S. (1999): Thermal stress modeling of freezing biological tissues. In: Advances in Heat and Mass Transfer in Biotechnology. IMECE 1999, Nashville, Tennessee. HTD-Vol. 363, BED-Vol. 44, pp. 183-188. Article (PDF 0.2MB)

Dennis, B.H., Dulikravich, G.S., Rabin, Y. (2000): Optimization of organ freezing protocols with specified allowable thermal stress levels. IMECE 2000, Orlando, FL, November 5-10, HTD-Vol. 368/BED-Vol. 47, pp. 33-48. Article (PDF 0.2MB)

Rabin, Y., Steif, P.S. (2000): Thermal stress modeling in cryosurgery. International Journal of Solids and Structures 37:2363-2375. Article (PDF 0.3MB)

Rabin, Y., Steif, P.S. (2005): Letter-to-the-Editor: Analysis of thermo-mechanical stress in cryopreservation, CryoLetters, 26(6):409-411 Article (PDF 0.1MB)

Steif, P.S., Palastro, M.C, Rabin, Y. (2007): Analysis of the effect of partial vitrification on stress development in cryopreserved blood vessels. Medical Engineering & Physics, 29:661-670 Article (PDF 0.5MB)

Rabin, Y., Steif, P.S (2006): Solid mechanics aspect of cryobiology. In: Advances in Biopresevation (Baust, J.G., and Baust J.M., Eds.), CRC Taylor & Francis, Chap. 13, pp. 359-382.

Steif, P.S., Palastro, M.C, Rabin, Y. (2007): The effect of temperature gradients on stress development during cryopreservation via vitrification. Cell Preservation Technology, 5(2):104-115 Article (PDF 0.2MB)

Steif, P.S., Palastro, M.C, Rabin, Y. (2008): Continuum mechanics analysis of fracture progression in the vitrified cryoprotective agent DP6. ASME Biomechanical Engineering, 130(2):021006 PubMed

Steif, P.S., Noday, D.A., Rabin, Y. (2009): Can thermal expansion differences between cryopreserved tissue and cryoprotective agents alone cause cracking? CryoLetters 30(6):414-421 PubMed

Experimental Solid Mechanics in Cryobiology

Rabin, Y., Steif, P.S., Taylor, M.J., Julian, T.B., Wolmark, N. (1996): An experimental study of the mechanical response of frozen biological tissues at cryogenic temperatures. Cryobiology, 33:472-482. Article (PDF 0.1MB)

Rabin, Y., Olson, P., Taylor, M.J., Steif, P.S., Julian, T.B., Wolmark, N. (1997): Gross damage accumulation in frozen rabbit liver due to mechanical stress at cryogenic temperatures. Cryobiology, 34:394-405. Article (PDF 1.9MB)

Rabin, Y., Taylor, M.J., Wolmark, N. (1998): Thermal expansion measurements of frozen biological tissues at cryogenic temperatures. ASME Journal of Biomechanical Engineering, 120(2):259-266. Article (PDF 1.6MB)

Rabin, Y., Bell, E. (2003): Thermal expansion measurements of cryoprotective agents. Part I: A new experimental apparatus. Cryobiology, 46:254-263. Article (PDF 1.4MB)

Rabin, Y., Bell, E. (2003): Thermal expansion measurements of cryoprotective agents. Part II: Measurements of DP6 and VS55, and comparison with DMSO. Cryobiology, 46:264-270. Article (PDF 0.9MB)

Plitz, J., Rabin, Y., Walsh, J. (2004): The effect of thermal expansion of ingredients on the cocktails VS55 and DP6. Cell Preservation Technology, 2(3):215-226. Article (PDF 1.9MB)

Rabin, Y., Plitz, J., (2005): Thermal expansion of blood vessels and muscle specimens permeated with DMSO, DP6, and VS55 in cryogenic temperatures. Annals of Biomedical Engineering, 33(9):1213-1228 Article (PDF 0.9MB)

Jimenez Rios, J.L., Rabin, Y. (2006): Thermal expansion of blood vessels in low cryogenic temperatures. Part I: A new experimental device, Cryobiology, 52(2):269-283 Article (PDF 0.5MB)

Jimenez Rios, J.L., Rabin, Y. (2006): Thermal expansion of blood vessels in low cryogenic temperatures. Part II: Measurements of blood vessels vitrified with VS55, DP6, and 7.05M DMSO, Cryobiology, 52(2):284-294 Article (PDF 0.2MB)

Jimenez-Rios, J.L., Steif, P.S., Rabin, Y. (2006): Experimental study of viscoelasticity effects in cryopreservation of blood vessels by means of vitrification. 5th World Congress on Biomechanics, Munich, Germany

Jimenez Rios, J.L., Rabin, Y. (2007): A New device for mechanical testing of blood vessels at cryogenic temperatures. Journal of Experimental Mechanics 47:337–346 (A special issue on  Mechanics of Organic, Implant, and Bioinspired Materials) Article (PDF 0.7MB)

Jimenez Rios, J.L., Steif, P.S., Rabin, Y., (2007): Stress-strain measurements and viscoelastic response of blood vessels cryopreserved by vitrification. Annals of Biomedical Engineering 35(12):2077-2086 Article (PDF 0.5MB)

Noday, D.A., Steif, P.S., Rabin, Y. (2009): Viscosity of cryoprotective agents near glass transition: a new device, technique, and data on DMSO, DP6, and VS55. Journal of Experimental Mechanics, 49(5):663-672 Article (PDF 0.5MB)

Eisenberg, D.P., Taylor, M.J., Rabin, Y. (2012): Thermal expansion of DP6 combined with synthetic ice modulators in presence and absence of biological tissues. Cryobiology, 65(2):117-25 PubMed

See also Temperature-Controlled Microscopy and Macroscopy

Uncertainty in Measurements and Mathematical Modeling

Rabin, Y. (1998): Uncertainty in temperature measurements during cryosurgery. CryoLetters, 19(4):213-224. Article (PDF 1.1MB)

Rabin, Y. (1998): Uncertainty in measurements of fluid temperature in tubes. CryoLetters, 19(5):319-326. Article (PDF 0.1MB)

Rabin, Y. (2003):  A general model for the propagation of uncertainty in measurements into heat transfer simulations and its application to cryobiology. Cryobiology, 46(2): 109-120. Article (PDF 1.9MB)

Temperature-Controlled Microscopy and Macroscopy

Rabin, Y., Podbilewicz, B. (2000): Temperature-controlled microscopy for imaging of living cells: apparatus, thermal analysis, and temperature dependency of embryonic elongation in Caenorhabditis elegans. Journal of Microscopy, 199(3): 214-223. Article (PDF 1.9MB)

Rabin, Y. (2000): Is it reasonable to assume a uniformly distributed cooling rate along the microslide of a directional solidification stage? Journal of Microscopy, 200(1):42-49. Article (PDF 1.0MB)

Rabin, Y., Taylor, M.J., Walsh, J.R., Baicu, S., Steif, P.S. (2005): Cryomacroscopy of vitrification, Part I: A prototype and experimental observations on the cocktails VS55 and DP6, Cell Preservation Technology, 3(3):169-183 Article (PDF 1.3MB) Selected images and experimental results

Steif, P.S., Palastro, M., Wen, C.R., Baicu, S., Taylor, M.J., Rabin, Y. (2005): Cryomacroscopy of vitrification, Part II: Experimental observations and analysis of fracture formation in vitrified VS55 and DP6, Cell Preservation Technology, 3(3):184-200 Article (PDF 1.6MB) Selected images and experimental results

Rabin, Y., Steif, P.S., Hess, K.C., Jimenez-Rios, J.L., Palastro, M.C. (2006): Fracture formation in vitrified thin films of cryoprotectants. Cryobiology, 53:75-95 Article (PDF 0.9MB) Selected images and experimental results

Baicu, S., Taylor, M.J., Chen, Z., Rabin, Y. (2006): Vitrification of carotid artery segments: An integrated study of thermophysical events and functional recovery towards scale-up for clinical applications. Cell Preservation Technology, 4(4):236-244 Article (PDF 5.6MB)

Baicu, S., Taylor, M.J., Chen, Z., Rabin Y. (2008): Cryopreservation of carotid artery segments via vitrification subject to marginal thermal conditions: Correlation of freezing visualization with functional recovery. Cryobiology, 58:1-8 Article (PDF 0.7MB)

Feig, J.S.G., Williams, A.C., Lin, C.C., Rabin, Y. (2012): Developing the cryomacroscope for cryopreservation applications. 38th Annual Northeast Bioengineering Conference, Philadelphia, PA (March 16-18) Extended Abstract (PDF 0.4MB)

Rabin, Y., Feig, J.S.G., Williams, A.C., Lin, C.C., Thaokar, C. (2012): Cryomacroscopy in 3D: a device prototype for the study of cryopreservation. ASME 2012 Summer Bioengineering Conference - SBC 2012, Fajardo, Puerto Rico, USA (June 20-23) Extended Abstract (PDF 0.3MB)

Temperature Measurements

Rabin, Y., Rittel, D. (1999): A model for the time response of solid-embedded thermocouples. Experimental Mechanics, 39(1):132-137. Article (PDF 0.1MB)

Rittel, D., Rabin, Y. (2000): An investigation of the heat generated during cyclic loading of two glassy polymers, Part II: Thermal analysis. Mechanics of Materials, 32(3):149-159. Article (PDF 0.3MB)

Rabin, Y., Rittel, D. (2000): Infrared temperature sensing of mechanically loaded specimens: Thermal analysis. Experimental Mechanics, 40(2):197-202. Article (PDF 0.1MB)

Zhang, S., Yang, Y., Barmak, K., Rabin, Y., Asheghi, M. (2004): MEMS based high sensitivity calorimetry, IMECE 2004, Anaheim, CA, USA, IMECE2004- 62332. Article (PDF 0.3MB)

Zhang, S., Rabin, Y., Yang, Y., Asheghi, M. (2007): Nanoscale calorimetry using a suspended bridge configuration, IEEE Journal of Microelectromechanical Systems. Article (PDF 0.9MB)

Khairi, A., Hung, S-C, Paramesh, J., Fedder, G., Rabin, Y. (2011): Ultra-miniature wireless temperature sensor for thermal medicine applications. Energy-based Treatment of Tissue and Assessment VI, SPIE – BiOS 2011, San Francisco, CA, USA (January 22-27).

Thaokar, C., Rabin, Y. (2011): Temperature field reconstruction for the application of wireless implantable temperature sensors in cryosurgery. Cryobiology 65(3):270-277 PubMed

Hyperthermia and Thermal Ablation

Rabin, Y. (2002): Is intracellular hyperthermia superior to extracellular hyperthermia in the thermal sense? International Journal of Hyperthermia, 18(3):194-202. Article (PDF 0.1MB)

Rabin, Y. (2002): Cancer treatment by electromagnetic activated nanoheaters. EurekaAlert!

Jacob, H., Rabin, Y. (2003): Temperature-controlled snare. US Patent No. 6,517,538 B1 Patent (PDF 0.5MB)

Thermal Effects during Bone Drilling

Lee, J.E, Rabin, Y., Ozdoganlar, O.B. (2011): A new thermal model for bone drilling with applications to orthopaedic surgery. Medical Engineering and Physics, 33(10):1234-44 Article (PDF 1.6MB)

Lee, J.E, Ozdoganlar, O.B., Rabin, Y.  (2011): An experimental investigation on bone temperatures elevation  during bone drilling, Medical Engineering and Physics, 34:1510-1520 Article (PDF 1.9MB)

 

______________________________________________

Copyright©