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Selected Publications in Biothermal Technology

       Ehrlich, L.E., Feig, J.S.G., Schiffres, S.N., Malen, J.A., Rabin, Y. (2015): Large thermal conductivity differences between the crystalline and vitrified state of DMSO with applications to cryopreservation, PlosONE

       Eisenberg, D.P., Rabin, Y. (2015): Stress-strain measurements in vitrified arteries permeated with synthetic ice modulators, ASME Journal of Biomechanical Engineering, in press PubMed

       Sehrawat, A., Keelan, R., Shimada, K., Wilfong, D.M., McCormick, J.T., Rabin, Y. (2015): Simulation-based cryosurgery intelligent tutoring system (ITS) prototype, Technology in Cancer Research and Treatment, in press PubMed

       Keelan, R., Zhang, H., Shimada, K., Rabin, Y. (2015):  GPU-based bioheat simulation to facilitate rapid decision making associated with cryosurgery training, Technology in Cancer Research and Treatment, in press PubMed

       Eisenberg, D.P., Steif, P.S., Rabin, Y. (2014): On the effects of thermal history on the development and relaxation of thermo-mechanical stress in cryopreservation, Cryogenics, 64:86–94 PubMed

       Furuhata, T., Song, I., Rabin, Y., Shimada, K. (2014): Interactive prostate shape reconstruction from 3D TRUS images, Journal of Computational Design and Engineering, 1(4):272-288 Download

       Khairi, A., Thaokar, C., Fedder, G., Paramesh, J., Rabin, Y. (2014): Characterization of a CMOS sensing core for ultra-miniature wireless implantable temperature sensors with application to cryomedicine, Medical Engineering and Physics, 36(9):1191–1196 PubMed

       Feig, J.S.G., Rabin, Y. (2014):  The scanning cryomacroscope with applications to cryopreservation – a device prototype, Cryogenics, 62:118–128 PubMed

       Eisenberg, D.P., Taylor, M.J., Jorge L. Jimenez-Rios, Rabin, Y. (2014): Thermal expansion of vitrified blood vessels permeated with DP6 and synthetic ice modulators, Cryobiology, 68(3):318-26 PubMed

       Feig, J.S.G., Rabin, Y. (2013):  Integration of polarized light into scanning cryomacroscopy. CRYO2013-the 50th  Annual Meeting of the Society for Cryobiology, N. Bethesda, DC (July 28-31), Cryobiology, 67(3):399-400 ScienceDirect

       Rabin, Y., Taylor, M.J., Feig, J.S.G., Baicu, S., Chen, Z. (2013): A new cryomacroscope device (Type III) for visualization of physical events in cryopreservation with applications to vitrification and synthetic ice modulators, Cryobiology 67(3):264-73 PubMed

       Keelan, R., Yamakawa, S., Shimada, K., Rabin, Y. (2013): Computerized Training of cryosurgery – a system approach, CryoLetters 34(4):324-337 PubMed

       Khairi, A., Wu, C, Rabin, Y., Fedder, G., Paramesh, J., Schwartzman, D. (2013): Ultra-low power frequency and duty-cycle modulated implantable temperature-pressure sensor. IEEE Biomedical Circuits and Systems Conference - BioCAS 2013, IEEE, pp. 226-229, Rotterdam, the Netherlands (October 31 – November 2)

       Ehrlich, L.E., Feig, J.S.G., Schiffres, S.N., Malen, J.A., Rabin, Y. (2013): A new device and technique for thermal conductivity measurements of glass-forming materials with application to cryopreservation. ASME 2013 Summer Bioengineering Conference - SBC 2013, Minneapolis, MN, USA (July 14-19)

       Rabin, Y., Feig, J.S.G., Williams, A.C., Lin, C.C., Thaokar, C. (2012): Cryomacroscopy in 3D: a device prototype for the study of cryopreservation. ASME 2012 Summer Bioengineering Conference - SBC 2012, Fajardo, Puerto Rico, USA (June 20-23) Download

       Sehrawat, A., Shimada, K., Rabin, Y. (2012): Generating prostate models by means of geometric deformation for the application of computerized training of cryosurgery. International Journal of Computer Assisted Radiology and Surgery, 8(2): 301-312 Download

       Thaokar, C., Rabin, Y. (2012): Temperature field reconstruction for the application of wireless implantable temperature sensors in cryosurgery, Cryobiology 65(3):270-277 PubMed

       Eisenberg, D.P., Taylor, M.J., Rabin, Y. (2012): Thermal expansion of DP6 combined with synthetic ice blockers in presence and absence of biological tissues. Cryobiology, 65(2):117-125 PubMed

       Lee, J.E, Ozdoganlar, O.B., Rabin, Y.  (2012): An experimental investigation on thermal exposure during bone drilling. Medical Engineering and Physics, 34:1510-1520 Download

       Lee, J.E, Rabin, Y., Ozdoganlar, O.B. (2011): A new thermal model for bone drilling with applications to orthopaedic surgery. Medical Engineering and Physics, 33(10):1234-44 Download

       Lee, J.E., Ozdoganlar, O.B., Rabin, Y. (2011): Analysis of heat transfer in bone drilling. ASME 2011 Summer Bioengineering Conference - SBC 2011, Farmington, PA, USA (June 22-25)

       Eisenberg, D.P., Rabin, Y. (2011): The effect of synthetic ice blockers on thermal expansion of the cryoprotective cocktail DP6. ASME 2011 Summer Bioengineering Conference - SBC 2011, Farmington, PA, USA (June 22-25)

       Keelan, R., Shimada, K., Rabin, Y. (2011): Developing a framework for computerized training of cryosurgery based on finite elements analysis. ASME 2011 Summer Bioengineering Conference - SBC 2011, Farmington, PA, USA (June 22-25)

       Thaokar, C., Rabin, Y. (2011): Temperature field reconstruction for the application of wireless implantable temperature sensors in cryosurgery. ASME 2011 Summer Bioengineering Conference - SBC 2011, Farmington, PA, USA (June 22-25)

       Sehrawat, A., Shimada, K., Rabin, Y. (2011): Geometric deformation of three-dimensional prostate model with applications to computerized training of cryosurgery. ASME 2011 Summer Bioengineering Conference - SBC 2011, Farmington, PA, USA (June 22-25)

       Khairi, A., Hung, S-C, Paramesh, J., Fedder, G., Rabin, Y. (2011): Ultra-miniature wireless temperature sensor for thermal medicine applications. Energy-based Treatment of Tissue and Assessment VI, SPIE – BiOS 2011, San Francisco, CA, USA (January 22-27) Link

       Rossi, M.R., Tanaka, D., Shimada, K., Rabin, Y. (2010): Computerized planning of prostate cryosurgery using variable cryoprobe insertion depth. Cryobiology 60(1):71-79 PubMed

       Rabin, Y. (2009): Computerized planning of cryosurgery: from model reconstruction to cryoprobe placement strategies. BiOS 2009, Energy-based Treatment of Tissue and Assessment V, San Jose, CA, USA (January 24-29) Download

       Noday, D.A., Steif, P.S., Rabin, Y. (2009): Viscosity of cryoprotective agents near glass transition: a new device, technique, and data on DMSO, DP6, and VS55. Journal of Experimental Mechanics, 49(5):663-672 Download

       Steif, P.S., Noday, D.A., Rabin, Y. (2009): Can thermal expansion differences between cryopreserved tissue and cryoprotective agents alone cause cracking? CryoLetters 30(6):414-421 PubMed

       Baicu, S., Taylor, M.J., Chen, Z., Rabin, Y. (2008): Cryopreservation of carotid artery segments via vitrification subject to marginal thermal conditions: Correlation of freezing visualization with functional recovery. Cryobiology, 57(1):1-8 Download

       Rossi, M.R., Tanaka, D., Shimada, K., Rabin, Y. (2008): Computerized planning of cryosurgery using bubble packing: an experimental validation on a phantom material. International Journal of Heat and Mass Transfer 51(23-24):5671-5678 Download

       Tanaka, D., Shimada, K., Rossi, M.R., Rabin, Y. (2008): Computerized planning of prostate cryosurgery with pullback procedure. Computer Aided Surgery, 13(1):1-13 PubMed

       Tanaka, D., Shimada, K., Rossi, M.R., Rabin, Y. (2008): Cryosurgery planning using bubble packing in 3D. Computer Methods in Biomechanics and Biomedical Engineering, 11(2):113-121 Download

       Rabin, Y. (2008): Key issues in bioheat transfer simulations for the application of cryosurgery planning. Cryobiology, 56(3):248-50 Download

       Steif, P.S., Palastro, M.C, Rabin, Y. (2008): Continuum mechanics analysis of fracture progression in the vitrified cryoprotective agent DP6. ASME Biomechanical Engineering, 130(2):021006 PubMed

       Rossi, M., Rabin, Y. (2007): Analysis of a numerical scheme for bioheat simulations of cryosurgery and its experimental validation on a phantom material. MSV'07-The 2007 International Conference on Modeling, Simulation and Visualization Methods, Las Vegas, Nevada (June 25-28) Download

       Zhang, S., Yang, Y., Rabin, Y., Barmak K., Asheghi, M. (2007): A novel experimental procedure and technique for small scale calorimetry. ASME-JSME Thermal Engineering Summer Heat Transfer Conference, HT2007-32894, Vancouver, British Columbia, Canada (July 8-12) Link

       Rossi, M.R., Tanaka, D., Shimada, K., Rabin, Y. (2007): An efficient numerical technique for bioheat simulations and its application to computerized cryosurgery planning. Computer Methods and Programs in Biomedicine, 85(1):41-50 Download

       Jimenez Rios, J.L., and Rabin, Y. (2007): A new device for mechanical testing of blood vessels at cryogenic temperatures. Journal of Experimental Mechanics 47:337–346 (Special issue on: Mechanics of Organic, Implant, and Bioinspired Materials) Download

       Tanaka, D., Rossi, M.R., Shimada, K., Rabin, Y. (2007): Towards intra-operative computerized planning of prostate cryosurgery. The International Journal of Medical Robotics and Computer Assisted Surgery, 3:10-19 Download

       Rossi, M.R., Rabin, Y. (2007): Experimental verification of numerical simulations of cryosurgery with application to computerized planning. Physics in Medicine and Biology 52:4553-4567 Download

       Steif, P.S., Palastro, M.C, Rabin, Y. (2007): The effect of temperature gradients on stress development during cryopreservation via vitrification. Cell Preservation Technology 5(2):104-115 Download

       Zhang, S., Rabin, Y., Yang, Y., Barmak, K., Asheghi, M. (2007): Nanoscale calorimetry using a suspended bridge configuration. IEEE Journal of Microelectromechanical Systems 16(14):861-871 Download

       Jimenez Rios, J.L., Paul S. Steif, and Rabin, Y. (2007): Stress-strain measurements and viscoelastic response of blood vessels cryopreserved by vitrification. Annals of Biomedical Engineering 35(12):2077-2086 Download

       Tanaka, D., Shimada, K., Rabin, Y. (2006): Two-phase Computerized Planning of Cryosurgery Using Bubble-packing and Force-field Analogy. ASME Journal of Biomechanical Engineering, 128(1):49-58 Download

       Jimenez Rios, J.L., Rabin, Y. (2006): Thermal expansion of blood vessels in low cryogenic temperatures, Part I: A new experimental device. Cryobiology, 52(2):269-283 Download

       Jimenez Rios, J.L., and Rabin, Y. (2006): Thermal expansion of blood vessels in low cryogenic temperatures, Part II: Measurements of blood vessels vitrified with VS55, DP6, and 7.05M DMSO. Cryobiology, 52(2):284-294 Download

       Rabin, Y., Steif, P.S., Hess, K.C., Jimenez-Rios, J.L., Palastro, M.C. (2006): Fracture formation in vitrified thin films of cryoprotectants. Cryobiology, 53:75-95 Download

       Baicu, S., Taylor, M.J., Chen, Z., Rabin, Y. (2006): Vitrification of carotid artery segments: An integrated study of thermophysical events and functional recovery towards scale-up for clinical applications. Cell Preservation Technology, 4(4):236-244 Download

       Steif, P.S., Palastro, M.C, Rabin, Y. (2006): Analysis of the effect of partial vitrification on stress development in cryopreserved blood vessels. Medical Engineering & Physics, 29(6):661-670 Download

       Rabin, Y., Steif, P.S. (2006): Solid mechanics aspect of cryobiology, In: Advances in Biopreservation (Baust, J.G., and Baust J.M., Eds.), CRC Taylor & Francis, Chap. 13, pp. 359-382

       Rabin, Y., Plitz, J. (2005): Thermal expansion of blood vessels and muscle specimens permeated with DMSO, DP6, and VS55 in cryogenic temperatures. Annals of Biomedical Engineering, 33(9):1213 – 1228 Download

       Rabin, Y., Taylor, M.J., Walsh, J.R., Baicu, S., Steif, P.S. (2005): Cryomacroscopy of vitrification, Part I: A prototype and experimental observations on the cocktails VS55 and DP6. Cell Preservation Technology, 3(3):169-183 Download

       Steif, P.S., Palastro, M., Wen, C.R., Baicu, S., Taylor, M.J., Rabin, Y. (2005): Cryomacroscopy of vitrification, Part II: Experimental observations and analysis of fracture formation in vitrified VS55 and DP6. Cell Preservation Technology, 3(3):184-200 Download

       Rabin, Y., Steif, P.S. (2005): Letter-to-the-Editor: Analysis of thermo-mechanical stress in cryopreservation. CryoLetters, 26(6):409-411 Download

       Lung, D.C., Stahovich, T.F., Rabin, Y. (2004): Computerized planning for multiprobe cryosurgery using a force-field analogy. Computer Methods in Biomechanics and Biomedical Engineering, 7(2):101-110 Download

       Rabin, Y., Lung, D.C., Stahovich, T.F. (2004): Computerized planning of cryosurgery using cryoprobes and cryoheaters. Technology in Cancer Research and Treatment, 3(3):227-243. Download

       Plitz, J., Rabin, Y., Walsh, J., (2004): The effect of thermal expansion of ingredients on the cocktails VS55 and DP6. Cell Preservation Technology, 2(3):215-226 Download

       Zhang, S., Yang, Y., Barmak, K., Rabin, Y., Asheghi, M. (2004): MEMS based high sensitivity calorimetry. International Mechanical Engineering Congress and Exposition 2004, Anaheim, CA (November 13-19) Download

       Rabin, Y., Stahovich, T.F. (2003): Cryoheater as a means of cryosurgery control. Physics in Medicine and Biology, 48:619-632 Download

       Rabin, Y. (2003): A general model for the propagation of uncertainty in measurements into heat transfer simulations and its application to cryobiology. Cryobiology, 46(2):109-120 Download

       Rabin, Y., Bell, E. (2003): Thermal expansion measurements of cryoprotective agents. Part I: A new experimental apparatus. Cryobiology, 46(3):254-263 Download

       Rabin, Y., Bell, E., (2003): Thermal expansion measurements of cryoprotective agents. Part II: Measurements of DP6 and VS55, and comparison with DMSO. Cryobiology, 46(3):264-270 Download

       Rabin, Y. (2002): Is intracellular hyperthermia superior to extracellular hyperthermia in the thermal sense? International Journal of Hyperthermia, 18(3):194-202 Download

       Rabin, Y., Stahovich, T.F. (2002): The thermal effect of urethral warming during cryosurgery. CryoLetters, 23:361-374 Download

       Rabin, Y. (2001): Imaging of breast cryosurgery. In: Atlas of Cryosurgery (Korpan, N.K., Ed.), Springer-Verlag, Vienna, Austria, pp. 344-353 Download

       Rabin, Y., Julian, T.B., Olson, P. (2001): Minimally invasive breast cryosurgery. In: Basics of Cryosurgery (Korpan, N.K., Ed.), Springer-Verlag, Vienna, Austria, pp. 213-223 Download

       Rittel, D., Rabin, Y. (2000): An investigation of the heat generated during cyclic loading of two glassy polymers, Part II: thermal analysis. Mechanics of Materials, 32(3):149-159 Download

       Rabin, Y., Steif, P.S. (2000): Thermal stress modeling in cryosurgery. International Journal of Solids and Structures 37:2363-2375 Download

       Rabin, Y., Rittel, D. (2000): Infrared temperature sensing of mechanically loaded specimens: thermal analysis. Experimental Mechanics, 40(2):197-202 Download

       Rabin, Y. (2000): The effect of temperature-dependent thermophysical properties in heat transfer simulations of biomaterials in cryogenic temperatures. Cryo-Letters, 21:163-170 Download

       Rabin, Y., Podbilewicz, B. (2000): Temperature-controlled microscopy for 4-D imaging of living cells: apparatus, thermal analysis, and temperature dependency of embryonic elongation in C. elegans. Journal of Microscopy, 199(3): 214-223 Download

       Rabin, Y. (2000): Is it reasonable to assume a uniformly distributed cooling rate along the microslide of a directional solidification stage? Journal of Microscopy, 200(1):42-49 Download

       Dennis, B.H., Dulikravich, G.S., Rabin, Y. (2000): Optimization of organ freezing protocols with specified allowable thermal stress levels. International Mechanical Engineering Congress and Exposition 2000, Orlando, FL, November 5-10, HTD-Vol. 368/BED-Vol. 47, pp. 33-48 Download

       Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1999): Cryosurgery for breast malignancies: apparatus and techniques. In: Advances in Heat and Mass Transfer in Biotechnology, International Mechanical Engineering Congress and Exposition 1999, Nashville, Tennessee. HTD-Vol. 363, BED-Vol. 44, pp. 65-69 Download

       Rabin, Y., Maytal, B-Z. (1999): Thermal analysis of cryocycling. Cryo-Letters, 20(2):95-102 Download

       Rabin, Y., Rittel, D. (1999): A model for the time response of solid-embedded thermocouples. Experimental Mechanics, 39(1):132-137 Download

       Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1999): Long-term follow-up post-cryosurgery in a sheep breast model. Cryobiology, 39:29-46 Download

       Rabin, Y., Steif, P.S. (1999): Thermal stress modeling of freezing biological tissues. In: Advances in Heat and Mass Transfer in Biotechnology, International Mechanical Engineering Congress and Exposition 1999, Nashville, Tennessee. HTD-Vol. 363, BED-Vol. 44, pp. 183-188 Download

       Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1999): Development of a cryosurgical technique for breast malignancies. SPIE Conference on Innovations in Breast Cancer Diagnosis and Minimally Invasive Therapy, San Jose, CA (January 23-29). SPIE 3590:465-471. Link

       Rabin, Y., Shitzer, A. (1998): Numerical solution of the multidimensional freezing problem during cryosurgery. ASME Journal of Biomechanical Engineering, 120(1):32-37 Download

       Rabin, Y. (1998): Uncertainty in temperature measurements during cryosurgery, Cryo-Letters, 19(4):213-224 Download

       Rabin, Y., Taylor, M.J., Wolmark, N. (1998): Thermal expansion measurements of frozen biological tissues at cryogenic temperatures. ASME Journal of Biomechanical Engineering, 120(2):259-266 Download

       Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1998): Evaluation of post cryosurgery injury in a sheep breast model using the vital stain 2,3,5-triphenyltetrazolium chloride. Cryo-Letters, 19(4):255-262 Download

       Rabin, Y., Steif, P.S. (1998): Thermal stresses in a freezing sphere and its application to cryobiology. ASME Journal of Applied Mechanics, 65(2):328-333 Download

       Rabin, Y. (1998): Uncertainty in measurements of fluid temperature in tubes. Cryo-Letters, 19(5):319-326 Download

       Rabin, Y., Shitzer, A. (1997): Combined solution to the inverse Stefan problem for successive freezing/thawing in non-ideal biological tissues. ASME Journal of Biomechanical Engineering, 119(2):146-152 Download

       Rabin, Y., Julian, T.B., Wolmark, N. (1997): A compact cryosurgical apparatus for minimal-invasive cryosurgery. Biomedical Instrumentation & Technology, 31:251-258 Download

       Rabin, Y., Olson, P., Taylor, M.J., Steif, P.S., Julian, T.B., Wolmark, N. (1997): Gross damage accumulation in frozen rabbit liver due to mechanical stress at cryogenic temperatures. Cryobiology, 34:394-405 Download

       Rabin, Y., Shitzer, A. (1996): A new cryosurgical device for controlled freezing, Part I: setup and validation test. Cryobiology, 33:82-92 Download

       Rabin, Y., Coleman, R., Mordohovich, D., Ber, R., Shitzer, A. (1996): A new cryosurgical device for controlled freezing, Part II: in vivo experiments on rabbits’ hind thighs. Cryobiology, 33:93-105 Download

       Rabin, Y., Steif, P.S. (1996): Analysis of thermal stresses around a cryosurgical probe. Cryobiology, 33:276-290 Download

       Rabin, Y., Steif, P.S., Taylor, M.J., Julian, T.B., Wolmark, N. (1996): An experimental study of the mechanical response of frozen biological tissues at cryogenic temperatures. Cryobiology, 33:472-482 Download

       Rabin, Y., Shitzer, A. (1995): Exact solution to the one dimensional inverse Stefan problem in non-ideal biological tissues. ASME Journal of Heat Transfer, 117(2):425-431 Download

       Rabin, Y., Korin, E. (1993): An efficient numerical solution for the multidimensional solidification (or melting) problem using a microcomputer. International Journal of Heat and Mass Transfer, 36(3):673-683 Download

 

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