First half of the course: microbial physiology and metabolism, fermentations and respiration, metabolic regulation, bioconversions, recombinant DNA methodology and gene cloning. Second half: separation and purification, kinetics and design of biological reactors, mass transfer limitations within cell suspensions, and control of fermentation processes. Lectures will cover aspects of accuracy and resolution, relative merits and limitations, selection criteria, and typical practical applications for these devices. Several laboratory demonstrations will be provided. Each student will be expected to submit a project report on a topic assigned in the beginning of the course.
