2016

  • Naserifar, N., LeDuc, P.*, Fedder, G.K.* Material Gradients in Stretchable Substrates toward Integrated Electronic Functionality Advanced Materials 28:3584-91(2016).
  • Egan, P., Cagan, J.*, Schunn, C.*, Chiu, F., Moore, J., LeDuc, P.* The D3 Methodology: Bridging Science and Design for Bio-Based Product Development. Journal of Mechanical Design 138: 081101 (13), (2016).
  • Warren, K.M, Mpagazehe, J.N., LeDuc, P.R.* and Higgs, C.F.* Geometric Effects in Microfluidics on Heterogeneous cell stress using an Eulerian–Lagrangian approach. Lab Chip 16: 593-598 (2016).
  • Warren, K.M, Islam, M.M., LeDuc, P.R.*, Steward, R.* 2D and 3D Mechanobiology in Human and Nonhuman Systems. ACS Appl. Mater. Interfaces 8: 21869−21882 (2016).


  • 2015

  • Egan, P., Sinko, R., LeDuc, P.R.*, Keten, S.* The Role of Mechanics in Biological and Bio-Inspired Systems. Nature Communications 6: 7418, DOI: 10.1038/ncomms8418 (2015).
  • Egan, P., Moore, J., Schunn, C.*, Cagan, J,*, LeDuc, P.* (2015) Emergent Systems Energy Laws for Predicting Myosin Ensemble Processivity. PLoS Computational Biology 11(4): e1004177. (2015)
  • Kang, J., Puskar, K.M., Ehrlicher, A.J., LeDuc, P.R., Schwartz, R.S. Structurally Governed Cell Mechanotransduction through Multiscale Modeling. Scientific Reports 5: 8622, DOI: 10.1038/srep08622 (2015).
  • Egan, P., Cagan, J,*, Schunn, C.*, LeDuc, P.* Synergistic Human-Agent Methods for Deriving Effective Search Strategies: The Case of Nanoscale Design. Research in Engineering Design 26:145-169 (2015)
  • Hazar, M., Kim, Y.T., Song, J., LeDuc, P.R.* Davidson, L.A.*, Messner, W.C.* 3D Bio-Etching of a Complex Composite-Like Embryonic Tissue. Lab-on-a-Chip 15: 3293-3299 (2015).
  • Egan, P., Schunn, C.*, Cagan, J.*, LeDuc, P.* "Improving Understanding and Design Proficiency of Complex Multi-level Biosystems Through Animation and Parametric Relationships Support" Design Science 1, e3 doi:10.1017/dsj.2015.3 (2016).
  • Song, J., Shawky, J.H., Kim, Y.T., Hazar, M., LeDuc, P.R.* Sitti, M.*, Davidson, L.A.*, Controlled Surface Topography regulates Collective 3D Migration by Epithelial-Mesenchymal Composite Embryonic Tissues. Biomaterials 58:1-9 (2015)
  • Steward, R.L., Tan, C., Cheng, C.M., LeDuc, P.R.* Cellular Force Signal Integration Through Vector Logic Gates. J Biomech. 48:613-620 (2015).
  • González, L.M., Ruder, W.C., Mitchell, A.P., Messner, W.C., * LeDuc, P.R. * Sudden Motility Reversal Indicates Sensing of Magnetic Field Gradients in Magnetospirillum magneticum AMB-1 strain. The ISME Journal-Nature Publishing Group 9:1399-1409 (2015)


  • 2014

  • Kim, Y.T., Hazar, M., Vijayraghavan, D., Song, J., Messner, W.C.*, Davidson, L.A.*, LeDuc, P.R.* Mechanochemical Actuators of Embryonic Epithelial Contractility Proceedings of the National Academy of Sciences (in press)
  • Sei, Y., Justus, K., LeDuc, P.R.*, Kim, Y.T.* Engineering Living Systems on Chips: From Cells to Human on Chips. Microfluidics and Nanofluidics 16, 907-920 (2014).
  • Gonzalez, L.M. Ruder, W.C., LeDuc, P.R.*, Messner, W.C.* Controlling Magnetotactic Bacteria through an Integrated Nanofabricated Metallic Island and Optical Microscope Approach.Scientific Reports 4, 4104 (2014).
  •  

    2013

  • Tan, C., Saurabh, S., Bruchez, M., Schwartz, R.*, LeDuc, P.R.* Molecular Crowding Shapes Gene Expression in Synthetic Cellular Nanosystems. Nature Nanotechnology 8, 602-608 (Cover, 2013).
  • Cheng, C.M., Kim, Y.T., LeDuc, P.R. Probing the Dynamic Responses of Individual Actin Filaments Under Fluidic Mechanical Stimulation via Microfluidics. Applied Physics Letters 102, 193704 (2013).
  • Kim, Y. T.*, LeDuc, P. R.*, & Messner, W. C.* Modeling and Control of a Nonlinear Mechanism for High Performance Microfluidic Systems. IEEE Transactions on Control Systems Technology: a Publication of the IEEE Control Systems Society 21, 203-211 (2013).
  • Egan, P.F., Cagan, J.*, Schunn, C.*, LeDuc, P.R.* Design Of Complex Biologically-Based Nanoscale Systems using Multi-Agent Simulations and Structure-Behavior-Function Representations. Journal of Mechanical Design 135 (6), 061005 (2013).
  •  

    2012

  • Ruder, W.C.*, LeDuc, P.R.* Cells Gain Traction in 3D. Proceedings of the National Academy of Sciences109, 11060-11061 (2012).
  • Tan, C., Lo, J., LeDuc, P.R.*, Cheng, C.-M.* Frontiers of Optofluidics in Synthetic Biology. Lab Chip 12, 3654-3665 (2012).
  • Kim, Y. T., Messner, W. C.* & LeDuc, P. R.* Disruptive Microfluidics: From Life Sciences to World Health to Energy. Disruptive Science and Technology 1: 41-53 (2012).
  • Ruder, W.C., Pratt, E.D., Brandy, N.Z.D., LaVan, D., LeDuc, P.R.*, &Antaki, J.A.* Calcium Signaling is Gated by a Mechanical Threshold in Three-Dimensional Environments. Scientific Reports 2, 554 (2012).
  • Didier, J.E., Schafer, C.M., & LeDuc, P.R.* Programmed Biologically Inspired Synthetic Templating of Multifunctional Nanoarchitectures for Small-Scale Reactions. European Journal of Inorganic Chemistry32, 5405-5410 (2012).
  • Lee, B., LeDuc, P.R., Schwartz, R. Three-Dimensional Stochastic Off-Lattice Model of Binding Chemistry in Crowded Environments. PLoS One 7, e30131 (2012).
  • Cassino, T.R., Drowley, L. Okada, M., Beckman, S.A., Keller, B., Tobita, K., LeDuc, P.R. & Huard, J. Mechanical Loading of Stem Cells for Improvement of Transplantation Outcome in a Model of Acute Myocardial Infarction: The Role of Loading History. Tissue Engineering Part A. 18, 1101-1108 (2012).
  • Ruder, W.C., Pratt, E.D., Bakhru, S., Sitti. M., Zappe, S., Cheng, C.M., Antaki, J.A.*, & LeDuc, P.R.* Three-Dimensional Microfiber Devices that Mimic Physiological Environments to Probe Cell Mechanics and Signaling. Lab Chip, 12, 1775-1779 (2012).
  • Ruder, W.C., Chia-Pei, D.H., Edelman, B.D., Schwartz, R.*, & LeDuc, P.R.* Biological Colloid Engineering: Self-Assembly of Dipolar Ferromagnetic Chains in a Functionalized Biogenic Ferrofluid. Appl. Phys. Lett. 101, 063701 (2012).
  •  

    2011

  • LeDuc, P.R.*, Messner, W.C.,* & Wikswo, J.P.* How Do Control-Based Approaches Enter into Biology? Annual Reviews of Biomedical Engineering 13, 369-396 (2011).
  • Kim, Y, Joshi, S.D., Messner, W.C.*, LeDuc, P.R.,* & Davidson, L.A.* Detection of Dynamic Spatiotemporal Response to Periodic Chemical Stimulation in a Xenopus Embryonic Tissue. PLoS ONE 6(1), e14624 (2011).
  • Li, Z., Zhang, Y., LeDuc, P.R., & Gregory, K.B. Microbial Electricity Generation via Microfluidic Flow Control. Biotechnology and Bioengineering 108, 2061-2069 (2011).
  • Zeng, Y., Lai, T., Koh, C., LeDuc, P. R.*, & Chiam, K. H.* Investigating Circular Dorsal Ruffles through Varying Substrate Stiffness and Mathematical Modeling. Biophysical Journal, 101, 2122-2130 (2011).
  • Kim, Y, Joshi, S.D., Davidson, L.A., LeDuc, P.R.,* & Messner, W.C.* Dynamic Control of 3D Chemical Profiles with a Single 2D Microfluidic Platform. Lab on a Chip 11, 2182-2188 (2011).
  • Wilson, M.E., Kota, N. Kim, Y., Wang, Y. Stolz, D., LeDuc, P.R. *, & Ozdoganlar, O.B.*, Fabrication of Circular Microfluidic Channels by Combining Mechanical Micromilling and Soft Lithography. Lab on a Chip 11, 1550-1555 (2011).
  • Cheng, C.-M., Dawson, J.T., Guo, Q., LeDuc, P.R.*, & Li, B.* Maskless fabrication of small-scale structures through controlling phase interactions. Applied Physics A 102, 185-188 (2011).
  • Kang, J., Steward, R.L., Kim, Y.T., Schwartz, R., LeDuc, P.R., Puskar, K.M., Response of an Actin Filament Network Model under Cyclic Stretching through a Coarse Grained Monte Carlo Approach. Journal of Theoretical Biology 274, 109-119 (2011).
  • Cheng, C.-M., LeDuc, P.R. Lin, Y.-W. Localized Bimodal Response of Neurite Extensions and Structural Proteins in Dorsal-Root Ganglion Neurons with Controlled Polydimethylsiloxane Substrate Stiffness. Journal of Biomechanics 44, 856-862 (2011).
  • Lee, B., LeDuc, P.R., Schwartz, R. Unified Regression Model of Binding Equilibria in Crowded Environments. Scientific Reports (Nature Publishing group) 1, 97 (2011).
  • Hazar, M., Steward, R. L., Chang, C. J., Orndoff, C. J., Zeng, Y., Ho, M. S., LeDuc, P. R., & Cheng, C. M.* Modulating Material Interfaces Through Biologically-inspired Intermediates. Applied Physics Letters, 99, 233701 (3) (2011).
  • Steward, R. L., Cheng, C. M., Ye, J. D., Bellin, R. M., & LeDuc, P. R.* Mechanical stretch and shear flow induced reorganization and recruitment of fibronectin in fibroblasts. Scientific Reports (Nature Publishing Group), 1(147), 1-12 (2011).
  • Chou, S., Cheng, C.-M., Lin, Y. W., Chen, C.-C.*, & LeDuc, P. R.* Localized Neurite Outgrowth Sensing through Micro-patterned Elastic Substrates. Soft Matter, 21, 9871-9877(2011).
  • Ruder, W.C.*, LeDuc, P.R.* Bioinspirations: Cell-Inspired Small-Scale Systems for Enabling Studies in Experimental Biomechanics. Integrative and Comparative Biology (Former journal name: American Zoologist) 51(1), 128-132 (2011).
  •  

    2010

  • Lin, Y.W., Bellin, R.M., Cheng, C.M., Steward, R., Cheng, Y.R., LeDuc, P.R.*, & Chen, C.C.,* Probing Localized Neural Mechanotransduction through Surface-Modified Elastomeric Matrices and Electrophysiology. Nature Protocols 714, 5 (4), 714-724 (2010).
  • Steward, R.L., Cheng, C.M., Wang, D.L., & LeDuc, P.R.* Probing Cell Structure Responses Through a Shear and Stretching Mechanical Stimulation Technique. Cell Biochem Biophys 56, 115-124 (2010).
  • Huang, X., Ni, J., Yan, LeDuc, P.R., Yao, J., Lin, Q. Thermally Tunable Polymer Microlenses for Biological Imaging. Journal of Microelectromechanical Systems, 19 (6), 1444-1449, 2010.
  • Singh, M., Gracio, J., LeDuc, P., Gonçalves, P., Marques, P., Gonçalves, G., Marques, F., Silva, V., Capela e Silva, F., Potes, J., Sousa, A. Integrated Biomimetic Carbon Nanotube Composites for In Vivo Systems. Nanoscale 2, 2855-2863 (2010)
  • Kim, Y.T., Pekkan, K., Messner, W.C.,* & LeDuc, P.R.* Three-Dimensional Chemical Profile Manipulation Using Two-Dimensional Autonomous Microfluidic Control. Journal of the American Chemical Society (JACS) 132, 1339-1347 (2010).
  • LeDuc, P.R.*, Messner, W.C.,* & & Wikswo, J.P.* How Do Controls Approaches Enter Into Biology? Annual Reviews of Biomedical Engineering (accepted).
  • Kim, Y, Joshi, S.D., Messner, W.C.*, LeDuc, P.R.,* Davidson, L.A.* Detection of Dynamic Spatiotemporal Response to Periodic Chemical Stimulation in a Xenopus Embryonic Tissue. PLoS ONE (accepted).
  • Wilson, M.E., Kota, N. Kim, Y., Wang, Y. Stolz, D., LeDuc, P.R.*, Ozdoganlar, O.B.*, Fabrication of Circular Microfluidic Channels by Combining Mechanical Micromilling and Soft Lithography. Lab on a Chip (accepted).
  • Kang, J., Steward, R.L., Kim, Y.T., Schwartz, R., LeDuc, P.R., Puskar, K.M., Response of an Actin Filament Network Model under Cyclic Stretching through a Coarse Grained Monte Carlo Approach. Journal of Theoretical Biology (accepted).
  • Cheng, C.-M., Dawson, J.T., Guo, Q., LeDuc, P.R.*, & Li, B.* Maskless fabrication of small-scale structures through controlling phase interactions. Applied Physics A (accepted).
  • Cheng, C.-M., LeDuc, P.R. Lin, Y.-W. Localized Bimodal Response of Neurite Extensions and Structural Proteins in Dorsal-Root Ganglion Neurons with Controlled Polydimethylsiloxane Substrate Stiffness. Journal of Biomechanics (accepted).
  • Steward, R.L., Cheng, C.M., Wang, D.L., & LeDuc, P.R.* Probing Cell Structure Responses Through a Shear and Stretching Mechanical Stimulation Technique. Cell Biochem Biophys 56, 115-124 (2010).
  • Huang, X., Ni, J., Yan, LeDuc, P.R., Yao, J., Lin, Q. Thermally Tunable Polymer Microlenses for Biological Imaging. Journal of Microelectromechanical Systems, 19 (6), 1444-1449 (2010).
  • Singh, M.*, Gracio, J., LeDuc, P., Gonçalves, P., Marques, P., Gonçalves, G., Marques, F., Silva, V., Capela e Silva, F., Potes, J., Sousa, A. Integrated Biomimetic Carbon Nanotube Composites for In Vivo Systems. Nanoscale, 2, 2855-2863 (2010).
  • Kim, Y.T., Pekkan, K., Messner, W.C.*, & LeDuc, P.R.* Three-Dimensional Chemical Profile Manipulation Using Two-Dimensional Autonomous Microfluidic Control. Journal of the American Chemical Society 132, 1339-1347 (2010).
  • Cheng, C.M., Lin, Y-W, Bellin, R.M., Cheng, C.M., Steward, R., Cheng, Y.-R., LeDuc, P.R.*, & Chen, C-C* Probing Localized Neural Mechanotransduction through Surface-Modified Elastomeric Matrices and Electrophysiology. Nature Protocols 5 (4), 714-724 (2010).
  •  

    2009 and earlier

    Please refer to here