Neutrinos are fundamental particles with no electrical charge, no color charge, and a very small (but nonzero) mass. They interact with other particles via the nuclear weak force, which is aptly named, so it's difficult to detect them directly; in fact, it took about a quarter of a century to detect them for the first time after their existence was predicted!
Coherent elastic neutrino-nucleus scattering (CEvNS), first proposed about forty years ago but never yet detected, is actually relatively common for a neutrino interaction with a cross section around 10-39 cm2. (Particle physicists measure the probability of a reaction occurring using the analogy of targets: a larger target, analogous to a larger cross-sectional area, is easier to hit.) In this process, a neutrino scatters from a nucleus by exchanging an electrically neutral Z boson. The scattering process is coherent: the neutrino interacts with the nucleus as a whole, rather than with individual nucleons or groups of nucleons. And it's elastic: a neutrino and a nucleus go in, and the same neutrino and the same nucleus come out, conserving kinetic energy. The problem is that even the lightest nucleus is literally hundreds of millions of times more massive than a neutrino. Even when the neutrino is carrying a fair amount of energy (50 MeV is a typical upper bound for nuclei of medium mass), the recoil imparted to the nucleus is quite small, hundreds of eV or a few keV. That's not easy to detect.
Luckily for CEvNs, though, a large community of physicists has spent decades designing and refining detectors to look for dark matter (specifically, WIMPs, or weakly interacting massive particles) via small nuclear recoils. In fact, the next generation of WIMP detectors will be so sensitive that they'll see a CEvNS background from solar neutrinos! So the time is right to make a dedicated measurement of CEvNS: detect the process, validate the models used in dark matter detection and supernova dynamics, and refine the measurement to look for the signature of new physics beyond the standard model. The COHERENT collaboration is preparing to make such a measurement at Oak Ridge National Laboratory, using the Spallation Neutron Source as a serendipitous source of pulsed neutrinos with the right energy range. COHERENT plans to measure CEvNS in at least three different detectors: cesium iodide, sodium iodide, and liquid argon (see more details on arXiv). Both the standard CEvNS cross section and the signatures of new physics will depend on the makeup of the target nuclei, making detector diversity a critical strategy. Now that a measurement has been accomplished in CsI (paper in Science) the other detectors are even more important.