Thesis Title

The Design of a Novel Distal Protection Filter and A In-Vitro Protocol for the Evaluation of Cerebral Protection Devices

Advisor

Ender Finol, PhD

 

Overview

Carotid Artery Disease occurs when artery† become clogged by athersclortic plaque build up. Carotid Artery Stenting, an non invasive intravenous procedure, is† used to treat Carotid Artery Disease.† During Carotid artery stenting, a stent is permanently† placed to in the artery to keep it open. During the stent placement an embolic protection device, preferably a† filter, is used to capture any plaque released during the procedure. The embolic protection filters increase the safety of the procedure by† diminishing the risk of a fatal perioperative stroke.

For my Masters research I designed a novel embolic protection device to minimize† the loss of captured emboli during retrieval and to allow the filter delivery system to cross the stenosis while minimizing the dislodgement of plaque. I also designed and constructed a novel bench top flow loop system to experimentally evaluate flow profiles using patient specific carotid artery models and commercially available embolic protection filters. This flow-loop system, after minor modification,† is currently being used at the Vascular Biomechanics and Biofluids Laboratory headed by Ender Finol, PhD at Carnegie Mellon University.

Publications

 

Accepted Conference Abstracts:

1. Design of a Novel Distal Protection Filter for Carotid Artery Stenting and an In Vitro Protocol for the Evaluation of Cerebral Protection Devices. (National Black Engineering Society National Conference 2006)

2. In vitro performance assessment of cerebral protection devices in carotid artery stenting (Transcatheter Cardiovascular Therapeutics 2005)

 

Published Literature:

1. Gaspard, S., Siewiorek, G.M., and Finol, E.A., 2006, "Experimental and computational flow modeling of cerebral protection devices for carotid artery stenting," Journal of Biomechanics, Vol. 39, Issue null, pp S308-S308.

2. Finol, E.A., Gaspard, S., and Wholey, M.H., 2005, "In vitro performance assessment of cerebral protection devices in carotid artery stenting," American Journal of Cardiology, Vol. 96, No. 7, Suppl. 1, pp. 146H.


Text Box: Home
Text Box: PhD 
Research
Text Box: Masters
Research
Text Box: Background
Text Box: TLneoCare

Sanna Gaspard

Masterís Research