Altered Trypsin Enzymes


     
 
           
 

     
 
           
Instructions:
  • Clicking on "Unmodified" loads the structure for the non-mutated or unmodified enzyme.
  • Clicking on "Trp1" loads the structure for the first mutant, "Trp2" loads the structure of the 2nd mutant, etc.
  • Clicking on "Simple View" shows the backbone atoms, a bound substrate (Ala-Ala-Arg-Ala-Ala) in thick sticks + spheres for atoms, and the sidechains of some important residues on the enzyme in thinner sticks.
  • +/- Sub will add and remove the substrate.
  • +/- Surf. on Sub will add or remove a gray surface on the substrate (be patient).
  • +/- Surface on triad will place a yellow surface over the three residues in the catalytic triad.
  • +/- Surface on #189 will place a red surface over the sidechain of residue 189.
Note:Labeling Atoms:
  1. Depress the right mouse button to get the pop-up menu.
  2. Select 'Set Picking'
  3. Select 'Label'
Now when you click on an atom, the label will appear in the Jmol window, next to the atom.