Wild-Type CSP

 

 Center 18  Highlight 18  zoom
Mutant CSP

 

Center 18  Highlight 18  zoom
Antibody-Hapten

 
 zoom



How to use this page for PS4:
The buttons below each window control the display in the above window.
Q2:
  • Use the structure of the CSP proteins to determine where the Ile (and its Ala substitution) are located in the protein.
  • Click on "Center on 18 to zoom in a bit, with residue 18 in the center.
  • Click on "Highlight 18" to put a transparent surface on residue 18.
Q3:
  • 'zoom' will give you a bigger view of the complex. The hypervariable loops are colored yellow (light chain) and cyan (heavy chain). Three sidechains from the antibody are shown in ball and stick and colored CPK (carbon light grey). The carbons on the bound hapten are colored dark grey.
  • 'Surface' will show the van der Waals radius of two residues that are involved with binding the hapten.
  • "Hapten +/-" will remove and add the hapten
  • "Hapten Surface +/-" will add a surface/remove to the hapten.