Feedback for Multiple Choice Quiz 18

  1. Competitive inhibitors act by binding to the enzyme active site. This specific binding usually requires a high degree of similarity between substrate and inhibitor.
  2. The first choice describes the mechanistic effect of noncompetitive inhibitors; the second describes the functional outcome of the effect.
  3. Since a competitve inhibitor can only affect KM it can only affect the x-intercept of the plot. the y-intercept is 1/VMAX.
  4. The apparent, or observed KM for a competitive inhibitor = αKM.
  5. Neither allosteric inhibitors nor allosteric activators bind at the active site. Enzyme regulators do not denature the enzyme. Inhibitors, by definition, slow the enzyme velocity. Inhibitors can be hydrophobic, hydrophlic, or amphiphilic. Hence, the second choice was the best. Allosteric inhibitors do not always participate in feedback regulation. (The keyword here is "usually".)
  All of the correct answers have a green check mark.
  Incorrect answers have the "red-lit" button next to your choice.