Feedback for Multiple Choice Quiz 10

  1. Limited digestion of an IgG molecule by papain results in selective cleavage at the neck of the "Y-shaped" molecule. See Fig. 14.23 for a diagram of the IgG molecule, but where the Fab and Fc portions are not identified!

  2. These are all important structural features of antibodies.

  3. The immunoglobulin fold is a supersecondary structure found in many proteins. It is found no less than 12 times in the IgG molecule.

  4. Fig. 14.23 does show this feature of the IgG molecule.

  5. The production of monoclonal antibodies is diagrammed in Fig. 14.26 where it is shown that mouse "cancer patients" are used.

  6. Antibodies can be selected to bind almost anything, but in nature the largest number of different epitopes result from the diverse surfaces of proteins.

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