Feedback for Multiple Choice Quiz 8

  All of the correct answers have a green check mark.
  Incorrect answers have the "red-lit" button next to your choice.

1. The most critical determinant of hydrogen bond strength is the distance between donor and acceptor atoms.

2. The net cost of breaking a hydrogen bond in regular secondary structure and reforming hydrogen bonds with water is about 2 KJ/mol. If these hydrogen bonds were not reformed the cost would be about 22 KJ/mol.

3. One of Pauling's postulates in proposing the α-helix was that all H-bonding groups would be satisfied. The same principle applies to all aspects of protein structure (and to the interaction of proteins with other molecules).

4. Van der Waals forces operate whenever atoms or molecules are near one another.

5. The free energy is inversely proportional to the dielectric constant of the medium. The dielectric constant of benzene is roughly 20-fold lower than that of water.

6. All of the above, except for a, are favourable for folding.

7. The correct answer is surrounded with silly statements!

8. Aside from the absolute nature of the incorrect statements, note that when charged residues are found in the protein interior, they almost always have another residue of opposite charge nearby.