Dr. Michael J. Taylor

Selected Publications

(Selected from more than 150 publications and patents)


Recent Reviews and Book Chapters

Taylor, M.J., and Brockbank, K.G.M. (2003):  “Frontiers in biopreservation technology: Challenges for the storage of living tissues and engineered constructs.”  In: Klatz, R. and Goldman, R. (eds.), Anti-Aging Medical Therapeutics, Volume 5. Chicago: A4M Publications, 2003:515-526. Article (PDF 0.4MB)

Taylor, M.J., Song, Y.C. and Brockbank, K.G.M. (2004): “Vitrification in Tissue Preservation: New Developments”. In: Benson, E., Fuller, B., and Lane, N. (eds.), Life in the Frozen State. London: CRC Press LLC, Boca Raton, Pp 603-641. Article (PDF 0.9MB)

Taylor, M.J., (2006): “Biology of Cell Survival in the Cold: The Basis for Biopreservation of Tissues and Organs”. Ch 2. In: Baust, J.G., and Baust, J.M. (eds)., Advances in Biopreservation. Boca Raton. CRC – Taylor &Francis. Pp 15-62. Article (PDF 1.6MB)

Brockbank, K.G. and Taylor, M.J. (2006): “Tissue Preservation”. Ch 8. In: Baust, J.G., and Baust, J.M. (eds), Advances in Biopreservation. Boca Raton. CRC – Taylor &Francis. Pp 157-196. Article (PDF 2.5MB)

Taylor M.J. (2007): “Hypothermia”. In: Fink, G., (Editor-in-Chief) Encyclopedia of Stress, 2nd Edition, Volume 2, Pp 428-438. Oxford: Academic Press. Article (PDF 0.4MB)

Taylor, M.J. (2007): Hypothermic Blood Substitution: Special considerations for protection of cells during ex vivo and in vivo preservation. Transfusion Med and Hemother, 34:226-244. Article (PDF 0.2MB)

Taylor, M.J., & Baicu, S. (2009): Review of vitreous islet cryopreservation: Some practical issues and their resolution. Organogenesis, 5(3):155-166. Article (PDF 0.9MB)

Joint Publications with Mechanical Engineering Faculty

Rabin, Y., Steif, P.S., Taylor, M.J., Julian, T.B., Wolmark, N. (1996): An experimental study of the mechanical response of frozen biological tissues at cryogenic temperatures. Cryobiology, 33:472-482. Article (PDF 0.1MB)

Rabin, Y., Olson, P., Taylor, M.J., Steif, P.S., Julian, T.B., Wolmark, N. (1997): Gross damage accumulation in frozen rabbit liver due to mechanical stress at cryogenic temperatures. Cryobiology, 34:394-405. Article (PDF 1.9MB)

Rabin, Y., Taylor, M.J., Wolmark, N. (1998): Thermal expansion measurements of frozen biological tissues at cryogenic temperatures. ASME Journal of Biomechanical Engineering, 120(2):259-266. Article (PDF 1.6MB)

Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1998): Evaluation of post cryosurgery injury in a sheep breast model using the vital stain 2,3,5-triphenyltetrazolium chloride. CryoLetters, 19(4):255-262. Article (PDF 2.6MB)

Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1999): Long-term follow-up post-cryosurgery in a sheep breast model. Cryobiology, 39:29-46. Article (PDF 0.6MB)

Rabin, Y., Julian, T.B., Olson, P., Taylor, M.J., Wolmark, N. (1999): Cryosurgery for breast malignancies: apparatus and techniques. In: Advances in Heat and Mass Transfer in Biotechnology. ASME IMECE 1999, Nashville, Tennessee. HTD-Vol. 363, BED-Vol. 44, pp. 65-70 Article (PDF 1.6MB)

Rabin, Y., Taylor, M.J., Walsh, J.R., Baicu, S., Steif, P.S. (2005): Cryomacroscopy of vitrification, Part I: A prototype and experimental observations on the cocktails VS55 and DP6, Cell Preservation Technology, 3(3):169-183 Article (PDF 1.3MB)

Steif, P.S., Palastro, M., Wen, C.R., Baicu, S., Taylor, M.J., Rabin, Y. (2005): Cryomacroscopy of vitrification, Part II: Experimental observations and analysis of fracture formation in vitrified VS55 and DP6, Cell Preservation Technology, 3(3):184-200 Article (PDF 1.6MB)

Baicu, S., Taylor, M.J., Chen, Z., Rabin, Y. (2006): Vitrification of carotid artery segments: An integrated study of thermophysical events and functional recovery towards scale-up for clinical applications. Cell Preservation Technology, 4(4):236-244 Article (PDF 5.6MB)

Baicu, S., Taylor, M.J., Chen, Z., Rabin Y. (2008): Cryopreservation of carotid artery segments via vitrification subject to marginal thermal conditions: Correlation of freezing visualization with functional recovery. Cryobiology, 58:1-8 Article (PDF 0.7MB)

Tissue and Organ Preservation (Since 2000)

Song, Y.C., Khirabadi, B.S., Lightfoot, F.G., Brockbank, K.G.M., and Taylor, M.J. (2000):  Vitreous cryopreservation maintains the function of vascular grafts.  Nature Biotechnology, 18:296-299. Article (PDF 4.7MB)

Song, Y.C., Hagen, P.O., Lightfoot, F.G., Taylor, M.J., Smith, A.C., and Brockbank, K.G. (2000):  In vivo evaluation of the effects of a new ice-free cryopreservation process on autologous vascular grafts.  J Invest Surg, 13:5:279-288. Article (PDF 8.8MB)

Ikonomovic, M., Kelly, K.M., Hentosz, T.M., Shih, S.R., Armstrong, D.M., and Taylor, M.J. (2001):  Ultraprofound Cerebral Hypothermia and Blood Substitution with an Acellular Synthetic Solution Maintains Neuronal Viability in Rat Hippocampus.  CryoLetters, 22:19-26. Article (PDF 3.1MB)

Taylor, M.J., Campbell, L.H., Rutledge, R.N., and Brockbank, K.G.M. (2001):  Comparison of unisol with euro-collins solution as a vehicle solution for cryoprotectants.  Transplantation Proc., 33:1-2:677-679. Article (PDF 0.8MB)

Baicu, S. and Taylor, M.J. (2002): Acid-base buffering in organ preservation solutions as a function of temperature: New parameters for comparing buffer capacity and efficiency. Cryobiology, 45:33-48. Article (PDF 5.0MB)

Song,Y.C., Lightfoot, F.G., Chen, Z., Taylor, M.J., and Brockbank, K.G.M. (2003): Vitreous Preservation of Rabbit Articular Cartilage. Cell Preservation Technology, 2(1):67-74. Article (PDF 2.5MB)

Baicu S.C., Simmons, B.A., Campbell, L.H., Taylor, M.J., and Brockbank, K.G.M. (2004): Interstitial fluid analysis for assessment of organ function. Clinical Transplantation 18(suppl.12):16-21. Article (PDF .1MB)

Taylor, M.J., Rhee, P., Chen, Z., and Alam, H.B. (2005): Design of preservation solutions for universal tissue preservation in vivo: demonstration of efficacy in pre-clinical models of profound hypothermic cardiac arrest. Transpl. Proc., 37:303-307. Article (PDF 1.8MB)

Baicu S.C., Taylor M.J., Brockbank K.G.M. (2006): The role of preservation solution on acid-base regulation during machine perfusion of kidneys. Clin. Transplant., 20:113-121. Article (PDF 0.2MB)

Baicu, S., Taylor, M.J., Brockbank, K.G.M. (2007): Modulating biochemical perturbations during 72-hour machine perfusion of kidneys: role of preservation solution. Cryobiology, 54:114-120. Article (PDF 0.2MB)

Taylor, M.J., Baicu, S., Leman, B., Greene, E., Vazquez, A., Brassil, J. (2008): 24-hour hypothermic machine perfusion preservation of porcine pancreas facilitates processing for islet isolation. Transplant Proc., 40:480-482. Article (PDF 0.1MB)

Weegman, B.P., Taylor, M.J., Baicu, S.C., Scott III, W.E., Mueller, K.R., Kitzman, J.D., Rizzari, M.D., Papas, K.K. Hypothermic Perfusion Preservation of Pancreas for islet grafts: validation using a split Lobe Porcine Model. Cell Medicine: part B Cell Transplantation. In press. Article (PDF 0.4MB)

Taylor, M.J., Baicu, S.C., Greene, E., Vazquez, A., Brassil, J. (2010). Islet Isolation From Juvenile Porcine Pancreas After 24-Hour Hypothermic Machine Perfusion Preservation. Cell Transplantation, 19:613-628. Article (PDF 4.5MB)

Taylor, M.J., Baicu, S.C. (2010). Current State of Hypothermic Machine Perfusion Preservation of Organs:The Clinical Perspective. Cryobiology, 60(3S):S20-S35. Article (PDF 0.6MB)

Taylor, M.J., Baicu, S.C. (2011). Hypothermic Perfusion of Pancreas: Emphasis on Preservation prior to Islet Isolation. In: Uygun K, Lee CY, editors. Organ Preservation and Reengineering. Boston: Artech House Publisher, 85-104. Article (PDF 0.3MB)

Taylor, M.J., Baicu, S.C. (2011). Cryo-isolation: A Novel new Method for Enzyme-Free Isolation of Pancreatic Islets Involving In Situ Cryopreservation of Islets and Selective Destruction of Acinar Tissue. Tranplant Proc, 43(9):3181-3183. Article (PDF 0.2MB)

 Suszynski, T.M., Rizzari, M.D., Scott III, W.E., Tempelman, L.A., Taylor, M.J., Papas, K.K. (2012): Persufflation (or Gaseous Oxygen Perfusion) as a Method of Organ Preservation. Cryobiology. In press. Article (PDF 1.3MB)

Taylor, M.J., Baicu, S.C. (2013). Non‐Enzymatic Cryogenic Isolation of Therapeutic Cells: Novel Approach for Enzyme‐Free Isolation of Pancreatic Islets Using In Situ Cryopreservation of Islets and Concurrent Selective Freeze Destruction of Acinar Tissue. Cell Transplantation. Article (PDF 0.8MB)

To the Biothermal Technology Laboratory

To Cell and Tissue Systems, Inc.

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