This project is aimed to simulate the hemodynamics of human cardiovascular, which provide a non-invasive way to investigate the intervention of advanced heart disease, as well as the therapy of rotary ventricular assist device.

[Cardiovascular Simulator, All Rights Reserved]
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Right ventricular (RV) failure is an important cause of morbidity and mortality after implantation of left ventricular assist device (LVAD). In order to identify patients who will benefit from LVAD support, this project developed a proganostic model using cost-sensitive decision tree based on retrospective analysis of patient data.

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Risk stratification in VAD candidates will facilitate the identification of potential patients beneficial from this advanced therapy and further guide the intervention time.

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A critical factor in the outcome of left ventricular assist device (LVAD) destination therapy is optimal patient
selection. Important risk scores have been developed to stratify LVAD patients; however, their impacts on
clinical practice have not been fully realized. We propose a user-centered decision guidance system (DGS) to adapt clinical work flow and further facilitate decision making of healthcare professionals.

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Morphogenesis of the “immature symmetric embryonic aortic arches” into the “mature and asymmetric aortic arches” involves a delicate sequence of cell and tissue migration, proliferation, and remodeling within an active biomechanical environment. Injection of flurescent dye into circulation of chick embryos at different development stage offers a decent way to observe the 2D morphogenesis of great vessels.

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Unique flow patterns in aortic arches: Aortic sac inlet blood flow distribution affects regional aortic arch perfusion.

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