Biomedical imaging, signal processing, and computational biology
As modern imaging techniques become increasingly sophisticated, accurate, and specific, it is clear that advances in our understanding of many complex biological processes (at the sub-cellular, tissue, and organ levels) will require the intelligent use of mathematical, computational, and algorithmic techniques to automatically extract and interpret the information present in microscopic images. In combination with the mission of our Center for Bioimage Informatics, the Lane Center for Computational Biology, and the Department of Biomedical Engineering at CMU, the focus of my research efforts is to work in close collaboration with biologists, physicians, as well as other experimental scientists, engineers, and mathematicians to
- identify important imaging related biological problems which could benefit from a more rigorous, quantitative, and mathematical formulation
- provide this formulation for such key problems
- provide computational tools for solving them
- disseminating these through appropriate collaborations, publications, and participation in international societies and conferences.
Selected presentations
- G.K. Rohde, A.J.S. Ribeiro, K.N. Dahl, R.F. Murphy, Deformation-based nuclear morphometry: Capturing nuclear shape variation in HeLa cells. Cytometry, vol 73A, pp. 341-350, 2008. paper, slides.
- G.K. Rohde, W. Wang, T. Peng, R.F. Murphy, Deformation-based nonlinear dimension reduction: applications to nuclear morphometry. Proceedings of the IEEE Int. Simp. on Biomedical Imaging, pp. 500-503, 2008. paper, slides.
- G.K. Rohde, D.M. Healy, Jr., A. Aldroubi, Sampling and reconstruction for biomedical image registration. Proceedings of the Forty-First IEEE Asilomar Conference on Signals, Systems & Computers, pp. 220-223, 2007. paper, slides.
- G.K. Rohde, D.M. Healy, Jr., C.A. Berenstein, A. Aldroubi, Interpolation artifacts in biomedical image registration, Proceedings of the IEEE Int. Simp. on Biomedical Imaging, pp. 648-651, 2007. paper, slides
- D.M. Healy, Jr., G.K. Rohde, Fast global image registration using random projections, Proceedings of the IEEE Int. Simp. on Biomedical Imaging, pp. 476-479, 2007. paper , slides .
- G.K. Rohde, D.M. Healy, Jr., C.A. Berenstein, A. Aldroubi, Measuring image similarity to sub-pixel accuracy, Proceedings of the IEEE Int. Simp. on Biomedical Imaging, pp. 638-641, 2006. paper , slides .
- G.K. Rohde, D.M. Healy, Jr., C.A. Berenstein, A. Aldroubi, D. Rockmore, Stochastic analysis of geometric image processing using B-splines, Proceedings of IEEE ICASSP, pp. 1017-1020, 2006. paper , slides .
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