Research Inserests

Academic Affiliations

Academic Background

Teaching

Honors & Awards

Publications: Journal Articles

1. Reis R. F., Yang G., Szpankowski L., Weaver C., Shah S. B., Robinson J. T., Hays T. S., Danuser G., Goldstein L. S. B., Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila (under review).
2. Gable A., Qiu M., Titus J., Balchand S., Ferenz N. F., Ma N., Fagerstrom C., Ross R. L., Yang G., Wadsworth P., Dynamic reorganization of Eg5 in the mammalian spindle throughout mitosis requires dynein and TPX2 (under review).
3. Roy S., Yang G., Tang Y., and Scott D. (2012) A simple photoactivation and image analysis module for visualizing and analyzing axonal transport with high temporal resolution, Nature Protocols, vol. 7, pp. 62-68, 2012.
4. Matov A., Edvall M.M., Yang G., and Gaudenz Danuser (2011), Optimal‐flow minimum-cost corres-pondence assignment in particle flow tracking, Computer Vision and Image Understanding, vol. 115, pp. 531-540.
5. Weinger J., Qiu M., Yang G., and Kapoor T. (2011) A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding, Current Biology, vol. 21, pp. 1-7.
6. Goodman B., Channels W., Qiu M., Iglesias P., Yang G.*, Zheng Y.* (2010) Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly, Journal of Biological Chemistry, vol. 285, pp. 35238-35244.
7. Houghtaling B.R., Yang G.*, Matov A.*, Danuser G., and Kapoor T. (2009) Op18 reveals the contribution of non-kinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle, Proceedings of the National Academy of Sciences, vol. 106, pp. 15338-15343.
8. Yang G.*, Cameron L.A.*, Danuser G., and Salmon E.D. (2008) Regional variation of microtubule flux reveals microtubule organization in Xenopus extract meiotic spindles, Journal of Cell Biology, vol. 182, pp. 631-639.
9. Yang G.*, Houghtaling B.R.*, Gaetz J., Liu J.Z., Danuser G., and Kapoor T.M. (2007), Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging, Nature Cell Biology, vol. 9, pp. 1233-1242. (*equal contribution)
10. Haghnia M., Cavalli V., Shah S.B., Schimmelpfeng K., Brusch R., Yang G., Herrera C., Pilling A., and Goldstein, L.S.B. (2007), Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment, Molecular Biology of the Cell, vol. 18, pp. 2081-2089.
11. Cameron L.A., Yang G., Cimini D., Canman J.C., Kisurina-Evgenieva O., Khodjakov A., Danuser G., and Salmon E.D. (2006) A pulling-in mechanism produces the majority of kinetochore microtubule poleward flux in PtK1 cells, Journal of Cell Biology, vol. 173, pp. 173-179. (Cover)
12. Yang G. and Nelson B.J. (2005) Optomechatronic design of microassembly systems for manufacturing hybrid microsystems, IEEE Transactions on Industrial Electronics, vol. 52, pp. 1013-1023. 1989
13. Yang G., Gaines J.A., and Nelson B.J. (2003) A supervisory wafer-level microassembly system for hybrid MEMS fabrication, Journal of Intelligent and Robotic Systems, vol. 37, pp. 43-68.
14. Vikramaditya B., Nelson B.J., Yang G., and Enikov E.T. (2001) Microassembly of hybrid magnetic MEMS, Journal of Micromechatronics, vol. 1, pp. 99-116.

Publications: Reviews & Book Chapters

1. Cameron, L.A., Houghtaling, B.R., and Yang G. (2010) Fluorescent Speckle Microscopy, in Optical Imaging Techniques: a Laboratory Manual, Yuste R. eds., Cold Spring Harbor Laboratory Press, pp. 667-682.
2. Applegate, K., Yang G., Danuser, G. (2009) High-content analysis of cytoskeleton functions by fluorescent speckle microscopy, Nanotechnology, vol. 5, Nanomedicine, Vogel V. et al. eds., pp. 167-206, Wiley-VCH.
3. Dorn J., Danuser G., and Yang G. (2007) Computational processing and analysis of dynamic fluorescence image data, in Fluorescent Proteins, Methods in Cell Biology, vol. 85, pp. 497-538.
4. Yang G. and Nelson, B.J. (2007) Fundamentals of microscopy and machine vision, in Life Science Automation: Fundamentals and Applications, Zhang M.J., Nelson B.J., and Felder R.A. eds., pp.125-149, Artech House.
5. Shah S., Yang G., Danuser G., and Goldstein L.S.B. (2006) Axonal transport: imaging and modeling of a neuronal process, in Proc. Nobel Symposium 131: Controlled Nanoscale Motion in Biological and Artificial Systems. Lecture Notes in Physics, vol. 711, pp. 65-84, Springer-Verlag.
6. Yang G. and Nelson B.J. (2003) Automated microassembly, in MEMS Packaging, T.-R. Hsu ed., pp. 109-140, IEE Press.

Publications: Peer Reviewed Conference Papers

1. Yang G. (2011) Nanometer resolution imaging and tracking of axonal cargo transport in normal and degenerative neurons (invited paper), Proc. 45th Annual Asilomar Conference on Signals, Systems, and Computers, to appear.
2. Yang G., Matov A., and Danuser G. (2005) Reliable tracking of large-scale dense particle motion for fluorescent live cell imaging. Proc. Workshop on Computer Vision Methods for Bioinformatics, IEEE Int. Conf. Computer Vision and Pattern Recognition. pp. 9-17.
3. Yang G. and Nelson B.J. (2003) Wavelet-based autofocusing and unsupervised segmentation of microscopic images. Proc. IEEE/RSJ Int. Conf. Intelligent Robots and Systems, vol. 3, pp. 2143-2148.
4. Yang G. and Nelson B.J. (2003) Micromanipulation contact transition control by selective focusing and microforce control. Proc. IEEE Int. Conf. Robotics and Automation, vol. 3, pp. 3200-3206.
5. Yang G. and Nelson B.J. (2002) Integration of microscopic vision and microforce feedback for microassembly. Proc. 3rd Int. Workshop on Microfactories, pp. 145-148.
6. Greminger M., Yang G., and Nelson B.J. (2002) Sensing nanonewton level forces by visually tracking structural deformations. Proc. IEEE Int. Conf. Robotics and Automation, vol. 2, pp. 1943-1948.
7. Yang G., Gaines J.A., and Nelson B.J. (2001) A flexible experimental workcell for efficient and reliable wafer-level 3D microassembly. Proc. IEEE Int. Conf. on Robotics and Automation, vol. 1, pp. 133-138.

Current Students