P. G. Campbell

Senior Research Scientist, Institute for Complex Engineered Systems, Carnegie Mellon University, Pittsburgh, Pennsylvania. Phone: 412-268-4126. FAX: 412-268-5229. Email: pcampbel@ices.cmu.edu

Education:

B. S., Animal Science, Auburn University (1978).
M. S., Animal Science, Auburn University (1981).
Ph.D., Physiology, The Pennsylvania State University (1988).

Professional Experience

1998-1993 Associate Research Scientist, Orthopaedic Research Laboratory, Allegheny-Singer Research Institute, Pittsburgh, Pennsylvania
1993-1998 Assistant Professor of Orthopaedic Surgery, Allegheny University of the Health Sciences, Allegheny Campus, Pittsburgh, Pennsylvania
1993-1998 Graduate Faculty, Department of Pathology, Graduate School of Medical Science, Allegheny University of the Health Sciences
1996-1998 Acting Director Orthopaedic Biochemistry and Biomechanics Laboratories, Allegheny University of the Health Sciences, Allegheny Campus, Pittsburgh, Pennsylvania
1998-present Visiting Senior Research Scientist, Institute for Complex Engineered Systems, Carnegie Mellon University, Pittsburgh, Pennsylvania

Research Activities:

Growth Factor Functional Gradients in Bone Defect Repair (Pennsylvania Infrastructure Technology Alliance); A System for Designing Engineered Bone Tissue (Carnegie Mellon Bioengineering Initiative); Noninvasive Optical In Vivo Imaging of Assisted and Non-Assisted Bone Regeneration in the Rat (Carnegie Mellon Bioengineering Initiative); Physical Modeling of Interstitial Transport of Growth Factors (Carnegie Mellon Bioengineering Initiative); Accelerating Recovery from Soft Tissue Injury Using IGF-I (NIH); Development and Assessment of Alternative Processes to Manufacture Composite Polymer/Ceramic Scaffold Materials (Pennsylvania Infrastructure Technology Alliance); Insulin-like Growth Factor-I Encapsulation in Polymer Scaffolds for Bone Tissue Engineering (Pennsylvania Infrastructure Technology Alliance); Role of Physical Environment in Migration of Bone Cells (NIH).

Representative Publications

Campbell PG, Andress DL (1997) Insulin-like growth factor (IGF)-binding protein-5-(201-218) region regulates hydroxyapatite and IGF-I binding. J Am J Physiol 273:E1005-E1013.

Powell DR, Durham SK, Liu F, Baker BK, Lee PDK, Watkins SL, Campbell PG, Brewer ED, Hintz RL, Hogg RJ. (1998) The IGF axis and growth in children with chronic renal failure. A Report of the Southwest Pediatric Nephrology Study Group. J Clin Endocrinol Metab 83:1654-1661.

Campbell PG, Durham SK, Suwanichkul A, Hayes JD, Powell DR. (1998) Plasminogen binds the heparin binding domain of insulin-like growth factor binding protein-3 Am J Physiol 275:E321-E331.

Durham SK, Suwanichkul A, Hayes JD, Herington AC, Powell DR, Campbell PG (1999) The heparin binding domain of insulin-like growth factor binding protein (IGFBP)-3 increases susceptibility of IGFBP-3 to proteolysis. Horm and Metab Res 31:216-225.

Marra KG, Campbell PG, DiMilla PA, Kumta P.N.; Mooney MP, Szem JW, Weiss LE (1999) "Novel Three Dimensional Biodegradable Scaffolds for Bone Tissue Engineering," Materials Research Society Symposium Proceedings, Biomedical Materials: Drug Delivery, Implants and Tissue Engineering, Ed. T Neenan, M Marcolongo, RT Valentini, 550, 155-160.

Kurtz CA, Loebig TG, Anderson DD, DeMeo PJ, Campbell PG. (1999) Insulin-like growth factor I accelerates functional recovery from Achilles tendon injury in a rat model. Am J Sports Med 27:363-369.