Biochemistry I Fall Term, 2004

THE STRUCTURE OF PROTEINS: TWO HYDROGEN-BONDED
HELICAL CONFIGURATIONS OF THE POLYPEPTIDE CHAIN

The title is from the paper by Pauling, Corey, & Branson published in
Proc. Nat'l. Acad. Sci. USA 37 pp. 205-212, (1951).

The pages indexed below are JPEG images of their classic paper. The authors described the structure of the a-helix. More important, they also explained in detail why they excluded other possible structures for the class of proteins they had investigated.

  1. First page.     Introduction
  2. Second page.     Fig. 1 and key peptide features
  3. Third page.     Figs. 2 & 3, the two proposed helices
  4. Fourth page.     Figs. 4 & 5, end views of the helices
  5. Fifth page.     Discussion of the helical features
  6. Sixth page.     Comparison to other proposals and Summary
  7. Seventh page.     End of the references cited
Each page has a JPEG image (480x800, ~100 K) with navigation links and a link to this index page at the bottom.

Alternatively, download the Pauling, Corey, & Branson paper as a PDF image from the Proc. Nat'l. Acad. Sci. USA site.

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